Tag Archives: drug discovery

Drug trial breakthrough shows that Ebola is ‘no longer incurable’

EARA Executive Director, Kirk Leech, looks at the remarkable progress in biomedical research in the search for a cure for Ebola virus which has devastated parts of central Africa in the last year.

This week, marking the first anniversary of the most recent Ebola outbreak, scientists running a clinical trial of new drugs in the Democratic Republic of the Congo (DRC) have announced a dramatic increase in survival rates.

For countries, such as the DRC, Liberia, Guinea, and Sierra Leone, Ebola is a serious health emergency. They are among the poorest countries in the world, only recently emerging from years of civil war and unrest that has left basic health infrastructures severely damaged or ruined. Living conditions are often restricted and unclean, water supplies are limited, medical treatment is scarce, and trust in officialdom, pretty much non-existent.

Massive underdevelopment and the attendant problem of political dysfunction have created a situation in which a virus like Ebola can flourish. Since 2014 a total of 28,616 cases of Ebola and 11,310 deaths were reported in Guinea, Liberia, and Sierra Leone. This is what is driving research into finding a way to halt the spread of the disease

Now, thanks in part to research involving mice and non-human primates the sponsors of the current clinical trial in DRC have announced a real breakthrough. While an experimental vaccine that was proven to be effective in monkeys had previously been shown to shield people from catching Ebola, this new development marks a first for people who have already been infected.

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Serendipity and Animal Research

Dr. Alberto Ferrari is a member of the managing board and of the scientific Committee of Pro-Test Italia, an association dedicated to correct scientific information on the topic of animal research in Italy. He has a Ph.D. in molecular medicine; during his training he has worked on animal models of psychiatric disorders. Currently, he is specializing in biostatistics and collaborates with the unity of medical statistics at the University of Pavia, Italy.

Animal experimentation has always drawn criticism from an ethical standpoint; but while concerns about animal welfare or good laboratory practice are legitimate (if not always easy to agree on), we know that the position of those who deem animal testing useless or dispensable from a strictly scientific point of view is much less acceptable.

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