Tag Archives: Annual Statistics

Cancer studies see rise in use of animals in Netherlands research

Increased biomedical research into cancer has seen a rise in the number of procedures using animals in the Netherlands, the latest statistics show.

The annual figures for 2017, show an overall increase in the number of animals used (in Dutch), with 530,568 procedures being conducted: 80,694 (17.9%) more than in 2016.

In 2017, more animal tests were conducted with zebrafish (research into anti-cancer drugs and an EU-funded project into hormone-disruptors that affect the human body) and mice (various investigations, particularly cancer research).

In addition, under a new EU reporting requirement, the number of animals that were bred, but were killed or died without being part of an animal test, was 448,252 animals, (see Additional Animals note).

The annual figures, have been released by the Dutch Food and Consumer Product Safety Authority (Nederlandse Voedsel- en Warenautoriteit, NVWA) in line with the requirements of EU law and demonstrates the continuing commitment of the Netherlands’ biomedical sector to research, as well as observing the principles of the ‘3Rs’ (Replacement, Refinement, Reduction) in the use of animals.

Wilbert Frieling, of the Dutch animal reseach advocacy group SID, said: ‘The use of animals is essential for biomedical research into diseases such as cancer and Parkinson’s and for vaccines – including the ones taken to protect us during overseas trips.

“Many of the cures and treatments we use today for conditions such as diabetes and pneumonia were made possible through the use of animals. The development of treatments and vaccines for animals also requires the experimental use of dogs and cats.’

Commenting on the figures, EARA Executive Director Kirk Leech said: ‘The publication of these figures shows that biomedical researchers in the Netherlands have nothing to hide. Behind each statistic is the story of basic research, of work towards combating disease and of improvements in human or veterinary medicine.’

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Notes to editors

Additional animals
Additional animals are those animals which were killed in the research setting without ever having undergone a regulated procedure. Examples of why this may happen include:
• Animals bred for tissue samples
• Animals that were bred for research, but could not be used. Reasons include:
– They were the wrong sex for the research.
– They were involved in creating or maintaining genetically altered lines, but did not
express the required genetic alteration (i.e. were born as wild types).
– The number was over and above the numbers needed for the research study (litter sizes can be unpredictable).
• Animals used to sustain inbred colonies (this includes breeding stock and neonatal losses)
• ‘Sentinel animals’ used for health screening of other animals in the laboratory

About EARA
The European Animal Research Association (EARA) is an organisation that communicates and advocates on biomedical research using animals and provides accurate, evidence-based information. It has more than 70 partner organisations, including private and public research bodies, universities, regional and national biomedical associations and suppliers, across 15 European countries.
EARA’s vision is to enhance the understanding and recognition of research involving animals across Europe, allowing for a more constructive dialogue with all stakeholders and a more efficient climate for research in Europe.

Spanish animal 2017 statistics shows drop in procedures

New figures released by the Spanish Ministry of Agriculture, Fisheries and Food, show an overall decrease in the use of animals in biomedical research last year.

According to the official government website (in Spanish), in 2017 there were a total of 802,976 procedures involving animals, which compares to 917,986 in 2016, .

Overall this reflects a significant drop, equivalent to one-eighth of the 2016 total number, including almost halving of the number of times fish were used (from 168,746 to 85,687).

The statistics, made available annually in compliance with European law, demonstrate the continuing commitment of the Spanish biomedical sector to working responsibly with animals used for research.

Particular trends show a reduction in the number of procedures on mice, rats, pigs and, especially cephalopods⸺down from 8444 to 20. More procedures on cats (531) and dogs (1476) occurred in 2017 than in the previous year. This overall downward trend countered the way the number of procedures in Spain had previously been increasing since 2014.

Commenting on the figures, Lluis Montoliu of the National Centre for Biotechnology, Spaintweeted: ‘It must be remembered … that the use of dogs is still indispensable in the preclinical validation of innovative gene therapy treatments for diseases and that the use of non-human primates is equally essential in certain pathologies that affect us.’

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‘Additional’ animal statistics now being published in EU

The UK has, this week, become the first country to submit ‘additional’ animal statistics under a new  EU reporting requirement.

The EU Directive on the protection of animals used for scientific purposes (2010/63) now requires that each EU country give details of the animals that are killed in research facilities that were not used in any regulated procedure.

Unlike the Annual Statistics, produced by EU countries, the additional numbers refer to the total number of animals which have been kept in the same regulated conditions, but without the potential of harm or suffering from scientific procedures. See here for further information.

The UK’s Additional Statistics for 2017 show that 1.81 million non-genetically altered (non-GA) animals were bred for scientific procedures, but were killed or died without being used in regulated procedure. 

The majority of these animals were mice (80%), rats (11%) and fish (7%) many of which were breeding animals used to sustain breeding groups.

Dr Sara Wells, of MRC Harwell, UK, welcomed the publication as a milestone in transparency and openness. “The broadening of the focus of the legislation will ensure that the scientific community and public are properly informed of the numbers of all animals involved in research”, she said.

Great Britain’s biomedical research statistics for 2017 indicate fewer animals used for second consecutive year

The latest figures released by the Home Office show a decrease in the overall use of animals in biomedical research in Great Britain’s public and private institutions.

These statistics for 2017 were presented to the UK Parliament under the terms of the Animals (Scientific Procedures) Act 1986 and demonstrate the continuing commitment of the British biomedical sector to openness and transparency about animal research, combined with an ongoing commitment to replace, reduce and refine the use of animals for every project, commonly known as the 3Rs.

The figures show that 3,789,373 experimental procedures were conducted in Great Britain [1] in 2017, 3.7% fewer than in 2016. Over 96% of the procedures on animals involved mice, fish, rats and birds while cats, dogs and non-human primates accounted for less than 0.2% of studies.

There was a significant fall in the number of procedures on dogs (3847 procedures) and on primates (2960 procedures), the lowest number for over 40 years for both species. Continue reading

Scientists in Europe must take more responsibility for openness, says EARA executive director

Openness and transparency surrounding the use of animals in research is ‘still an Achilles Heel’ for the biomedical sector, a roundtable hosted by the Federation of European Academies of Medicine (FEAM) last week has heard.

Speaking at the meeting, EARA Executive Director, Kirk Leech, said: “The zeitgeist is openness and transparency for the biomedical sector, but this is still an Achilles Heel for many European institutions.” Continue reading

Germany sees 7% rise in animal research procedures in 2016

This article first appeared in Speaking of Research 06/02/18

Germany’s Federal Ministry of Food and Agriculture (Bundesministerium für Ernährung und Landwirtschaft) has produced its 2016 annual statistics on animal research procedures for Germany. These statistics have seen some big changes from previous years and we will attempt to show comparisons according to the different methodologies used. Germany produces two sets of data as part of the Animal Protection Act.

  • 7(2) – procedures on animals
  • 4(3) – animals killed solely for tissues or organs without any prior procedures

A mouse procedure

Historically, Germany has used data from animals used under both §7(2) and §4(3) of the Animal Protection Act to create a dataset of animals used in research. This dataset was broken down by varying categories including use, severity, genetic status and more. This year, while the old totals can be seen, the main datasets are numbers of procedures on animals, excluding animals killed for tissues or organs (under §4(3)). This newer methodology puts Germany in line with the EU reporting requirements for animals in research – allowing for easier comparisons between countries.

In 2016, Germany reported 2,189,261 procedures on animals, up 7.1% from 2015. The number of animals is slightly lower at 2,131,448 (due to some animals being used in more than one procedure during 2016). Continue reading

Dutch animal research statistics: 18% more procedures than in 2013

The Netherlands Food and Consumer Product Safety Authority (Nederlandse Voedsel- en Warenautoriteit, NVWA) published Zo doende 2014, its annual report of animal research in the Netherlands, yesterday. The number of animals used is 17.9% higher than in 2013. Despite the annual report containing revised numbers for 2013, direct comparison is difficult due to new reporting requirements following on from the European Directive 2010/63/EU. Continue reading

The case for proactive communications of animal statistics

Every year the United Kingdom’s Home Office (the UK ministerial department of internal affairs) publishes its statistics on animals used in scientific procedures. The statistics are announced at a press briefing at which journalists can question the numbers of animals used and researchers place them in their scientific context. Now a yearly opportunity to openly discuss the need for animals in research, these press briefings were first organised as a counterweight to a negative, one-sided narrative as promoted by anti-animal research activists. Continue reading