Increased biomedical research into cancer has seen a rise in the number of procedures using animals in the Netherlands, the latest statistics show.
In 2017, more animal tests were conducted with zebrafish (research into anti-cancer drugs and an EU-funded project into hormone-disruptors that affect the human body) and mice (various investigations, particularly cancer research).
In addition, under a new EU reporting requirement, the number of animals that were bred, but were killed or died without being part of an animal test, was 448,252 animals, (see Additional Animals note).
The annual figures, have been released by the Dutch Food and Consumer Product Safety Authority (Nederlandse Voedsel- en Warenautoriteit, NVWA) in line with the requirements of EU law and demonstrates the continuing commitment of the Netherlands’ biomedical sector to research, as well as observing the principles of the ‘3Rs’ (Replacement, Refinement, Reduction) in the use of animals.
Wilbert Frieling, of the Dutch animal reseach advocacy group SID, said: ‘The use of animals is essential for biomedical research into diseases such as cancer and Parkinson’s and for vaccines – including the ones taken to protect us during overseas trips.
“Many of the cures and treatments we use today for conditions such as diabetes and pneumonia were made possible through the use of animals. The development of treatments and vaccines for animals also requires the experimental use of dogs and cats.’
Commenting on the figures, EARA Executive Director Kirk Leech said: ‘The publication of these figures shows that biomedical researchers in the Netherlands have nothing to hide. Behind each statistic is the story of basic research, of work towards combating disease and of improvements in human or veterinary medicine.’
Notes to editors
Additional animals are those animals which were killed in the research setting without ever having undergone a regulated procedure. Examples of why this may happen include:
• Animals bred for tissue samples
• Animals that were bred for research, but could not be used. Reasons include:
– They were the wrong sex for the research.
– They were involved in creating or maintaining genetically altered lines, but did not
express the required genetic alteration (i.e. were born as wild types).
– The number was over and above the numbers needed for the research study (litter sizes can be unpredictable).
• Animals used to sustain inbred colonies (this includes breeding stock and neonatal losses)
• ‘Sentinel animals’ used for health screening of other animals in the laboratory
The European Animal Research Association (EARA) is an organisation that communicates and advocates on biomedical research using animals and provides accurate, evidence-based information. It has more than 70 partner organisations, including private and public research bodies, universities, regional and national biomedical associations and suppliers, across 15 European countries.
EARA’s vision is to enhance the understanding and recognition of research involving animals across Europe, allowing for a more constructive dialogue with all stakeholders and a more efficient climate for research in Europe.